Omega 6 Fatty Acids are involved in the balance of inflammation.Omega 3 Fatty Acids are essential for brain function and cardiovascular health and are anti-inflammatory.Add-on Essential and Metabolic Fatty Acids Markers (Bloodspot- whole blood).Oxidative Stress Markers (urine) include the oxidative damage markers lipid peroxides and 8-OHdG.Dietary Peptide Related Markers can indicate incomplete protein breakdown and meat intake.Glycine/Serine Metabolites are involved in the serine-to-choline pathway and the methylation pathways.Urea Cycle Markers are byproducts associated with nitrogen (ammonia) detoxification.B Vitamin Markers are involved in biochemical reactions that specifically require B vitamins.Intermediary Metabolites are byproducts of amino acid metabolism.Nonessential Amino Acids are synthesized by the body.Essential Amino Acids must be derived from dietary sources.Oxalate Markers relate to kidney stone formation, oxidative stress and metabolic dysfunction.Toxin & Detoxification Markers relate to certain toxic metabolites and the body’s detoxification capacity.Vitamin Markers are specific analytes used to assess functional levels of vitamin cofactors.Neurotransmitter Metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine.Cellular Energy & Mitochondrial Metabolites are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle.
Malabsorption and Bacterial/ Yeast Dysbiosis Markers are metabolites produced by the gastrointestinal microbiome. Interpretation-At-A-Glance pages provide nutritional educational support for you and your patient highlighting the function of each nutrient, cause of deficiency, complications of deficiency and food sources of the nutrient. Nutrient Need Overview with recommendations for antioxidants, B-vitamins, minerals, essential fatty acids, GI support, and amino acids. Functional Imbalance Scores in areas of methylation, toxic exposure, mitochondrial dysfunction, fatty acid imbalances, and oxidative stress. Personalized Results Overview and Nutrient Need Overview. The Metabolomix+ Profile report categorizes results into several metabolic areas (see sample report for individual analytes): Several diseases are associated with abnormal organic acid, amino acid, and fatty acid levels such as depression, anxiety, cardiovascular disease, neurocognitive decline, diabetes, cancer, anorexia, and many others. Which patients might benefit from functional nutritional testing?Ĭommon clinical indications for testing include: Insights gained from the Metabolomix+ nutritional test allows clinicians to target nutritional therapies to meet the precise needs of their patients. A first morning void (FMV) urine collection, with optional add-on bloodspot finger stick and buccal swab, the Metabolomix+ nutritional test is a non-invasive, patient-friendly way to assess the functional need for antioxidants, B-vitamins, minerals, digestive support, fatty acids, and amino acids. The Metabolomix+ is a unique combination of nutritional tests that provides an analysis of key nutritional biomarkers. Urocanic acid absorbs UV light and is thought to act as a natural sunscreen.Metabolomix+: A Non-Invasive Personalized Nutritional Assessment Interestingly, histadine can also be broken down to form urocanic acid in the liver and skin. With these beneficial effects, histidine supplementation has been shown to improve insulin resistance, reduce BMI, suppress inflammation, and lower oxidative stress in obese women with metabolic syndrome. Histidine also inhibits the production of proinflammatory cytokines by monocytes and is therefore anti-inflammatory and antioxidant. 
This may impair digestion, since histamine binds to H2 receptors located on the surface of parietal cells to stimulate gastric acid secretion, necessary for protein breakdown. With this, decreased amounts of histidine and insufficient vitamin B6 can subsequently lead to a decrease in histamine concentration. The amino acid histadine becomes histamine via a vitamin B6- dependent enzyme called histidine decarboxylase. Histidine and histamine have a unique relationship. Other food sources include poultry, fish, nuts, seeds, and grains. Red meat is a common source of carnosine, and therefore histadine. Histidine is a semi-essential amino acid which is formed in the breakdown of carnosine.
0 kommentar(er)
